What Causes High Blood Sugar Without Diabetes
Written By
Blen Shumiye, MD
High blood sugar, also known as hyperglycemia, isn’t only a concern for people living with diabetes. You can experience elevated blood sugar even if you haven’t been diagnosed with diabetes. Understanding the causes can help you take action early, prevent complications, and support your overall metabolic health.
In this guide, we’ll explore the main factors that can raise your blood sugar, what to watch for, and how small lifestyle adjustments may make a difference.
What Is High Blood Sugar and Why Does It Matter?
Blood sugar refers to the glucose circulating in your bloodstream. Your body uses glucose for energy, but it needs insulin, a hormone produced by your pancreas to move glucose from your blood into your cells.
When your blood sugar rises above normal, even temporarily, it’s called hyperglycemia. Persistent hyperglycemia can stress your body, increase inflammation, and over time, contribute to insulin resistance. This means your body becomes less efficient at using insulin, which may increase your risk for metabolic problems down the line.
You may not notice high blood sugar immediately, but some subtle signs include:
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Feeling unusually thirsty
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Frequent urination
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Fatigue or low energy
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Headaches or difficulty concentrating
These signs aren’t always obvious, which is why understanding the underlying causes is important.
Can Your Diet Cause High Blood Sugar Even Without Diabetes?

Yes. What you eat directly impacts your blood sugar. Even if you don’t have diabetes, eating large amounts of refined carbohydrates, sugary snacks, or sweetened drinks can lead to spikes.
Some common dietary triggers include:
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White bread, pasta, and rice
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Pastries, cookies, and candy
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Sugary beverages like soda, sweet tea, or energy drinks
Frequent high sugar intake can gradually impair your insulin sensitivity, making your body work harder to regulate glucose. Over time, this may lead to prediabetes if left unaddressed.
Tip: Pairing carbs with protein, fiber, or healthy fats can help reduce blood sugar spikes after meals.
How Can Dehydration Affect Your Blood Sugar?
Dehydration reduces the amount of water in your blood, which concentrates glucose and temporarily raises blood sugar levels. Even mild dehydration can make it harder for your kidneys to remove excess glucose.
Signs of dehydration:
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Dark urine or reduced urination
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Dry mouth and lips
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Fatigue or dizziness
Prevention tip: Drink water throughout the day. A simple rule is to aim for clear to light yellow urine, which usually indicates adequate hydration.
Does Stress Really Raise Blood Sugar?

Yes. Stress triggers your body to release cortisol and adrenaline, hormones that prepare you for a “fight or flight” response. These hormones increase glucose production in your liver and reduce insulin sensitivity.
When stress becomes chronic:
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Blood sugar may stay elevated even when you’re resting
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You may feel tired, irritable, or have trouble sleeping
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You may crave high-carb “comfort” foods
Helpful strategies:
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Mindful breathing or meditation
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Regular exercise
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Journaling or speaking with a counselor
Can Medications Cause High Blood Sugar?
Certain medications can raise blood sugar temporarily or long-term, even in people without diabetes. Some common examples include:
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Corticosteroids (used for inflammation or autoimmune conditions)
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Some diuretics (water pills)
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Certain psychiatric medications
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Some hormonal therapies
If you take any of these medications, it’s wise to monitor your blood sugar, especially if you notice symptoms like unusual thirst or fatigue.
How Does Physical Inactivity Affect Blood Sugar?
Your muscles help regulate blood sugar by absorbing glucose when you move. A sedentary lifestyle can reduce this glucose uptake and increase your risk of insulin resistance.
Ways to stay active:
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Brisk walking for 30 minutes a day
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Strength training or bodyweight exercises 2–3 times per week
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Short movement breaks if you have a desk job
Even moderate activity after meals can help control post-meal blood sugar spikes.
Does Sleep Impact Your Blood Sugar?

Yes. Poor sleep or insufficient sleep disrupts hormones that regulate glucose. Sleep deprivation can:
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Increase hunger and cravings for sugary foods
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Reduce insulin sensitivity
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Lead to higher fasting blood sugar
Tips for better sleep:
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Maintain a consistent sleep schedule
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Limit screens 1–2 hours before bed
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Keep your bedroom cool, dark, and quiet
You can also check out our article on: Is Feeling Sleepy After Eating a Sign of Diabetes?
Can Hormonal Changes Affect Blood Sugar?
Hormonal fluctuations, such as during pregnancy, menopause, or conditions like polycystic ovary syndrome (PCOS), can influence blood sugar regulation.
How hormones play a role:
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Estrogen and progesterone affect insulin sensitivity
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Stress hormones like cortisol may rise during hormonal imbalance
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Thyroid issues can also influence glucose metabolism
Monitoring your blood sugar during times of hormonal change can help you catch patterns early.
Can Illness or Infection Raise Blood Sugar?
Yes. Your body sees illness or infection as a stressor, releasing hormones to fight it. These hormones can increase glucose levels temporarily.
Things to keep in mind:
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Fever or infection can cause higher fasting blood sugar
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Your body may need more insulin naturally to fight the illness
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Hydration and rest are important during recovery
How Does Genetics Play a Role?
Family history matters. If your parents or siblings have diabetes or metabolic syndrome, you may be predisposed to higher blood sugar. Genetics can influence:
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How your body produces and uses insulin
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Your risk for insulin resistance
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Your likelihood of developing prediabetes
Even with a genetic predisposition, lifestyle choices can significantly reduce your risk.
Can Caffeine Affect Blood Sugar?
Caffeine can raise blood sugar temporarily in some people by increasing stress hormone levels. Effects vary depending on your sensitivity and the amount you consume.
Tips:
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Track your blood sugar after coffee or energy drinks
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Try moderation 2–3 cups per day is usually safe
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Consider timing caffeine earlier in the day to avoid sleep disruption
How Can You Monitor Your Blood Sugar at Home?
Even without diabetes, monitoring your blood sugar can provide valuable insights. At-home testing options include:
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Fingerstick blood glucose monitors
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Continuous glucose monitors (CGMs)
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At-home lab kits from trusted providers
Regular monitoring can help you identify patterns and make informed lifestyle adjustments.
What Lifestyle Changes Can Help Keep Blood Sugar in Check?
Even small adjustments can make a difference:
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Balanced diet: Focus on fiber, lean protein, and healthy fats
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Regular activity: Aim for at least 150 minutes of moderate exercise weekly
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Hydration: Drink water consistently throughout the day
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Stress management: Meditation, yoga, or journaling
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Adequate sleep: 7–9 hours per night
Making incremental changes is often more sustainable than attempting a complete lifestyle overhaul.
When Should You Seek Medical Advice?
See a healthcare professional if you notice:
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Persistent high blood sugar readings
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Unexplained fatigue or weight changes
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Increased thirst or frequent urination
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Family history of diabetes
Early assessment can help prevent long-term complications and provide guidance on lifestyle strategies or monitoring tools.
Final Thoughts
High blood sugar without diabetes can be caused by many factors, including diet, hydration, stress, medications, inactivity, sleep, hormonal changes, illness, genetics, and caffeine intake. The good news is that you can often manage these factors proactively.
By staying mindful of your lifestyle choices, monitoring your blood sugar, and making gradual, evidence-based changes, you can protect your metabolic health and reduce your risk of future complications.
Next steps: Consider trying Ribbon Checkup’s urine test to monitor your levels conveniently from home and gain actionable insights for your health.
Related Resources
References
Amin, M., Zahra VAHDAT SHARIATPANAHI, Davoud VAHABZADEH, Zakaria VAHABZADEH, NASIRI, L., & SHARGH, A. (2017). Non-diabetic Hyperglycemia and Some of Its Correlates in ICU Hospitalized Patients Receiving Enteral Nutrition. Mædica, 12(3), 174. https://pmc.ncbi.nlm.nih.gov/articles/PMC5706756/
Blood sugar levels can fluctuate for many reasons. (2025). Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/diabetes/expert-answers/glucose-levels/faq-20424316
CDC. (2024, July 19). 10 Surprising Things That Can Spike Your Blood Sugar. Diabetes. https://www.cdc.gov/diabetes/living-with/10-things-that-spike-blood-sugar.html
Eggelbusch, M., Charlton, B. T., Bosutti, A., Ganse, B., Giakoumaki, I., Grootemaat, A. E., Hendrickse, P. W., Jaspers, Y., Kemp, S., Kerkhoff, T. J., Noort, W., van Weeghel, M., van der Wel, N. N., Wesseling, J. R., Frings-Meuthen, P., Rittweger, J., Mulder, E. R., Jaspers, R. T., Degens, H., & Wüst, R. C. I. (2024). The impact of bed rest on human skeletal muscle metabolism. Cell Reports Medicine, 5(1), 101372. https://doi.org/10.1016/j.xcrm.2023.101372
Zimlich, R. (2023, November 9). High Blood Sugar Symptoms in People Without Diabetes. Healthline; Healthline Media. https://www.healthline.com/health/high-blood-sugar-without-diabetes
Dr. Blen is a seasoned medical writer and General Practitioner with over five years of clinical experience. She blends deep medical expertise with a gift for clear, compassionate communication to create evidence-based content that informs and empowers. Her work spans clinical research, patient education, and health journalism, establishing her as a trusted voice in both professional and public health spheres.